眞弓　あずさ助教（本学附属北部医療センター）

専門領域 小児血液学・造血幹細胞移植
学会認定医
  • 日本小児科学会小児科専門医・指導医
  • 日本血液学会血液専門医・指導医
  • 日本小児血液がん学会小児血液・がん専門医
  • 日本がん治療認定医機構がん治療認定医
  • 日本造血・免疫細胞療法学会造血細胞移植認定医
  • 日本輸血・細胞治療学会認定医

受賞歴

  • 2021年

    The 4th International Cancer Research Symposium Young Investigator Award

  • 2022年

    公益信託日本白血病研究基金一般研究賞

  • 2022年

    日本小児がん研究グループ（JCCG）おおまさり研究助成　

研究内容

  1. 難治性白血病における融合遺伝子の機能解析と新規治療の探索

代表的論文

  1. Mayumi A, Imamura T, Yoshida H, Osone S, Yasuda T, Iehara T. Leukaemic cells expressing ETV6::FRK are sensitive to dasatinib in vivo. eJHaem. 2023; (in press).

  2. Mayumi A, Tomii T, Kanayama T, Mikami T, Tanaka K, Ueno H, Yoshida H, Kato I, Kawamura M, Nakahata T, Takita J, Hosoi H, Imamura T. The combination of ruxolitinib and Bcl-2/Mcl-1 inhibitors has a synergistic effect on leukemic cells carrying a SPAG9::JAK2 fusion. Cancer Gene Ther. 2022; 29: 1930-1938.

  3. Teramoto M, Maruyama S, Tamaki H, Kaida K, Mayumi A, Fukunaga K, Inoue T, Yoshihara K, Yoshihara S, Ikegame K, Okada M, Osugi Y, Ogawa H, Higasa S, Morita K, Matsumoto K, Kijima T. Association between the pharmacokinetics of rabbit anti-thymocyte globulin and acute graft-versus-host disease in patients who received haploidentical hematopoietic stem cell transplantation. Int J Hematol. 2022; 116: 248-257.

  4. Higuchi K, Sawada A, Kondo O, Okada Y, Tsujimoto H, Ioi A, Mayumi A, Shimizu M, Sato M, Goto K, Inoue S, Yasui M, Inoue M. HLA-haploidentical peripheral blood stem cell transplantation following reduced-intensity conditioning with very low-dose antithymocyte globulin for relapsed/refractory acute leukemia in pediatric patients: a single-institution retrospective analysis. Int J Hematol. 2022; 115: 406-413.

  5. Tomii T, Imamura T, Tanaka K, Kato I, Mayumi A, Soma E, Yano M, Sakamoto K, Mikami T, Morita M, Kiyokawa N, Horibe K, Adachi S, Nakahata T, Takita J, Hosoi H. Leukemic cells expressing NCOR1-LYN are sensitive to dasatinib in vivo in a patient-derived xenograft mouse model. Leukemia. 2021; 35: 2092-2096.

  6. Ikegame K, Kaida K, Fukunaga K, Osugi Y, Yoshihara K, Yoshihara S, Ishii S, Fujino S, Yamashita T, Mayumi A, Maruyama S, Teramoto M, Inoue T, Okada M, Tamaki H, Ogawa H, Fujimori Y. Allogeneic hematopoietic stem cell transplantation from a 2-HLA-haplotype-mismatched family donor for posttransplant relapse: a prospective phase I/II study. Bone Marrow Transplant. 2021; 56: 70-83.

  7. Mayumi A, Yamashita T, Matsuda I, Hikosaka K, Fujino S, Norose K, Kato Y, Hirota S, Nakajima T, Ogawa H, Ikegame K. Toxoplasmic Encephalitis Followed by Primary EBV-Associated Post-Transplant Lymphoproliferative Disorder of the Central Nervous System in a Patient Undergoing Allogeneic Hematopoietic Stem Cell Transplant: A Case Report. Transplant Proc. 2020; 52: 2858-2860.

  8. Mayumi A, Sawada A, Sato M, Shimizu M, Ioi A, Higuchi K, Yasui M, Kawa K, Inoue M. Impact of melphalan dose during reduced-intensity conditioning on engraftment of cord blood transplantation for chronic Epstein-Barr virus-associated T or NK cell lymphoproliferative diseases. Pediatr Blood Cancer. 2020; 67: e28536.

  9. Kanayama T, Imamura T, Mayumi A, Soma E, Sakamoto K, Hayakawa F, Tanizawa A, Kiyokawa N, Hosoi H. Functional analysis of a novel fusion protein PAX5-KIDINS220 identified in a pediatric Ph-like ALL patient. Int J Hematol. 2020; 112: 714-719.

  10. Mayumi A, Imamura T, Sakamoto K, Takeshi Ota, Shinya Osone, Ikuya Usami, Hajime Hosoi. Successful treatment with 2-chlorodeoxyadenosine of refractory pediatric Langerhans cell histiocytosis with initial involvement of the gastrointestinal tract. Int J Hematol. 2019; 110: 756-762.

  11. Mayumi A, Sawada A, Ioi A, Higuchi K, Shimizu M, Sato M, Yasui M, Inoue M. Intrathecal Infusion of Haploidentical Nondonor Lymphocytes for Central Nervous System Leukemic Relapse After Haploidentical Hematopoietic Stem Cell Transplantation. J Pediatr Hematol Oncol. 2018; 40: e129-e132.

  12. Sawada A, Shimizu M, Isaka K, Higuchi K, Mayumi A, Yoshimoto Y, Kikuchi H, Kondo O, Koyama-Sato M, Yasui M, Kawa K, Inoue M. Feasibility of HLA-haploidentical hematopoietic stem cell transplantation with post-transplantation cyclophosphamide for advanced pediatric malignancies. Pediatr Hematol Oncol. 2014; 31: 754-64.