戸澤　雄紀学内講師

専門領域 小児神経学
学会認定医
  • 小児科専門医・指導医
  • 小児神経専門医
  • てんかん専門医・指導医
  • 臨床遺伝専門医

経歴

  • 平成15年3月

    近畿大学医学部卒業

  • 平成15年4月

    京都府立医科大学附属病院 小児科研修医

  • 平成16年4月

    済生会滋賀県病院　小児科研修医

  • 平成17年4月

    済生会滋賀県病院　小児科医員

  • 平成18年4月

    市立福知山市民病院　小児科医員

  • 平成23年3月

    京都府立医科大学大学院修了（小児発達医学）

  • 平成23年4月

    綾部市立病院　小児科医長

  • 平成26年4月

    綾部市立病院　小児科部長

  • 平成29年4月

    京都府立医科大学小児科学教室助教

  • 令和5年4月

    京都府立医科大学小児科学教室　学内講師

学会役員歴

  • 日本小児神経学会　評議員・倫理委員会委員長

所属学会

  • 日本小児科学会
  • 日本小児神経学会
  • 日本てんかん学会
  • 日本人類遺伝学会

受賞歴

  • 平成25年

    第23回京都府立医科大学学友会青蓮賞（脳に発現するジストロフィン遺伝子の研究）

研究内容

  1. 発達性てんかん性脳症の分子病態解析

  2. 脊髄性筋萎縮症に対するSMN非依存的治療の探索

代表的論文

  1. Takada R, Tozawa T, Yamanaka T, Moroto M, Iehara T, Chiyonobu T. Bilateral choroid plexus resection in a 9p hexasomy/tetrasomy mosaic patient. Human Genome Var. 11(1):9, 2024.

  2. Taura Y, Tozawa T, Fujimoto T, Ichise E, Chiyonobu T, Itho K, Iehara T. Myosin Va, a novel interaction partner of STXBP1, is required to transport Syntaxin1A to the plsma membrane. Neuroscience. 524:256-268, 2023.

  3. Taura Y, Tozawa T, Isoda K, Horai S, Chiyonobu T, Yano N, Hayashi T, Yoshida T, Iehara T. Leigh-like syndrome with progressive cerebellar atrophy caused by novel HIBCH variants. Human Genome Var. 10(1):23, 2023.

  4. Tozawa T, Nishimura A, Ueno T, Shikata A, Taura Y, Takeshi Y, Nakagawa N, Wada T, Kosugi S, Uehara T, Takenouchi T, Kosaki K, Chiyonobu T. Complex hereditary spastic paraplegia associated with episodic visual loss caused by ACO2 variants. Hum Genome Var. 8(1):4, 2021.

  5. Tozawa T, Kasai T, Tatebe H, Shiomi K, Nishio H, Tokuda T, Chiyonobu T. Intrathecal nusinersen treatment after ventriculoperitoneal shunt placement: A case report focusing on the neurofilament light chain in cerebrospinal fluid. Brain Dev. 42(3):311-314, 2020.

  6. Takada R, Tozawa T, Kondo H, Kizaki Z, Kishita Y, Okazaki Y, Murayama K, Ohtake A, Chiyonobu T. Early infantile-onset Leigh syndrome complicated with infantile spasms associated with the m.9185T>C variant in the MT-ATP6 gene: Expanding the clinical spectrum. Brain Dev. 42(1):69-72, 2019.

  7. Hasegawa T, Yamada K, Tozawa T, Chiyonobu T, Tokuda S, Nishimura A, Hosoi H, Morimoto M. Cerebellar peduncle injury predicts motor impairment in preterm infants: A quantitave tractography study at term-equivalent age. Brain Dev. 40(9): 743-752, 2018.

  8. Tozawa T, Nishimura A, Ueno T, Kaneda D, Miyanomae Y, Chiyonobu T, Morimoto M, Hosoi H. A 5-year follow-up of triple seronegative myasthenia gravis successfully treated with tacrolimus therapy. Neuropediatrics. 49: 200-203, 2018.

  9. Tozawa T, Yokochi K, Kono S, Konishi T, Yamamoto T, Nishimura A, Chiyonobu T, Morimoto M, Hosoi H. A video report of brain-lung-thyroid syndrome in a Japanese female with a novel frameshift mutation of the NKX2-1 gene. Child Neurology Open. 3: 1-5, 2016.

  10. Moroto M, Nishimura A, Morimoto M, Isoda K, Morita T, Yoshida M, Morioka S, Tozawa T, Hasegawa T, Chiyonobu T, Yoshimoto K, Hosoi H. Altered somatosensory barrel cortex refinement in the developing brain of Mecp2-null mice. Brain Research. 1537: 319-326, 2013.

  11. Tozawa T, Itoh K, Tando S, Umekage M, Dai H, Hosoi H, Fushiki S. The shortest isoform of dystrophin (Dp40) interacts with a group of presynaptic proteins to form a presumptive novel complex in the mouse brain. Mol Neurobiol. 45(2): 287-297, 2012.

  12. Hasegawa T, Yamada K, Morimoto M, Morioka M, Tozawa T, Isoda K, Murakami A, Chiyonobu T, Tokuda T, Nishimura A, Nishimura T, Hosoi H. Development of corpus callosum in preterm infants is affected by the prematurity: in vivo assessment of diffusion tensor imaging at term-equivalent age. Pediatr Res. 69: 249-254, 2011.

  13. Kato S, Itoh K, Yaoi T, Tozawa T, Yoshikawa Y, Yasui H, Kanamura N, Hoshino A, Manabe N, Yamamoto K, Fushiki S. Organ distribution of quantum dots after intraperitoneal administration, with special reference to area-specific distribution in the brain. Nanotechnology. 21: 335103(7pp), 2010.

  14. Isoda K, Morimoto M, Matsui F, Hasegawa T, Tozawa T, Morioka S, Chiyonobu T, Nishimura A, Yoshimoto K, Hosoi H. Postnatal changes in serotonergic innervation to the hippocampus of methyl-CpG-binding protein 2-null mice. Neuroscience. 165: 1254-1260, 2010.